No Smoking Facility. Our New Mexico casino is open 24/7 daily. A warm and friendly environment with slot machines at the Main Casino. Sunday - Thursday: 8 AM - 2 AM | Friday & Saturday: Join the fun at Santa Ana Star Casino Hotel, the best casino in New Mexico! Located just north of Albuquerque, NM, we offer Gaming, Bowling, Golf, Dining. It's a warm, friendly environment with slot machines. Read More! Sky City's Main Casino and the Travel Center's Slot Area is open 24 hours daily. Upcoming Events. #1 Best Value of 24 Mexico Casino Hotels ; 2. Must be 21+. Indulge. Learn More. Colorful bingo cards and round bingo balls w/numbers. The Travel center includes a casino area with 45 slot machines. Win. #2 Best Value of 24 Mexico. Swirls of Cash. Saturdays in. at Isleta Resort & Casino. New Mexico has 23 Indian casinos and 4 Indian gaming travel centers located across 10 counties. Experience Vegas at Albuquerque's Sandia Casino! Test your luck at our slots or play poker, roulette & more! High limit & VIP lounge available. DISCOVER NORTHERN NEW MEXICO AT ITS BEST! The casino is open every day. Seadust Cancun Family Resort · 6, reviews. 1. . Open 24 hours, 7 days a week! What's happening. The Pyramid Cancun · 4, reviews. Excite. These casinos and gaming sites are owned by 14 New Mexico. Unwind. Sky City Casino is open 24 hours daily. With three live entertainment venues, you'll find something around every corner.